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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of age-related macular degeneration (AMD)
ncRNA name hsa-miR-23a
ncRNA Category miRNA
Disease name age-related macular degeneration (AMD)
Species Homo sapiens
Tissues/Cell_line RPE cells
Methods qRT-PCR, Northern blot, transfection, MTT assay, ELISA, luciferase reporter assay, Western blot
Expression pattern down-regulated
Functional description miR-23a expression was significantly downregulated in macular RPE cells from AMD eyes. The protection of RPE cells against oxidative damage is afforded by miR-23a through regulation of Fas.
PubMed ID 21693609
Year 2011
Title Effect of miR-23 on oxidant-induced injury in human retinal pigment epithelial cells.
Drug-related ncRNA NO

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