ncRNA name | hsa-miR-23a |
ncRNA Category | miRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Homo sapiens |
Tissues/Cell_line | RPE cells |
Methods | qRT-PCR, Northern blot, transfection, MTT assay, ELISA, luciferase reporter assay, Western blot |
Expression pattern | down-regulated |
Functional description | miR-23a expression was significantly downregulated in macular RPE cells from AMD eyes. The protection of RPE cells against oxidative damage is afforded by miR-23a through regulation of Fas. |
PubMed ID | 21693609 |
Year | 2011 |
Title | Effect of miR-23 on oxidant-induced injury in human retinal pigment epithelial cells. |
Drug-related ncRNA | NO |
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